The elastic ribbon description of DNA
For stretches of DNA longer than 20 basepairs, it is infeasible
to run atomistic level simulations. In our reduced order model, all-atoms
structure is replaced by a continuous twisted rod model which inherits
the influence of the sequence of basepairs via a naturally bent reference
state.
|
|
|
All-atoms
|
Twisted rod
|
The same reduction is applied to a 200 bp minicircle bound to a
small protein.
PF, 24 mars 2000