In polymer science, there is an ever-growing need for
mesoscale models, which - in some of their properties - do behave like atomistically realistic, rather than, generic models. The development of mappings between atomistic and mesoscopic models is a combination of the creative invention of suitable models and the menial labour of parameterising them. We have, therefore, developed methods to automatically parameterise mesoscale models against the results of atomistic calculations. Target properties to be reproduced in the process can be thermodynamic or structural. The first few applications (polymers in the melt and in solution) are discussed.